IgE rheumatoid factor

IgE and IgE-rheumatoid factors in circulating immune complexes in rheumatoid arthritis.

The sera of 21 patients with rheumatoid arthritis (RA), 11 patients with systemic lupus erythematosus (SLE), and 20 healthy subjects were analysed for the presence of IgE in immune complex fractions. These fractions were isolated by polyethylene glycol precipitation and gel filtration. Thirteen sera from RA patients contained IgE immune complexes (IC) and 11 of these were from patients with ext...

Rheumatoid arthritis : Looking Beyond Rheumatoid Factor

762 IntroductIon Rheumatoid arthritis (RA) is a chronic crippling disease that causes significant morbidity and even mortality. The etiology is not known and hence the diagnosis is based on the typical clinical picture of inflammatory symmetrical polyarthritis supported by imaging and serological investigations. Among the serological investigations, rheumatoid factor (RF) is the most widely use...

Reactivity between rheumatoid factor and rheumatoid tissue.

Differential Expression of Rheumatoid Factor-Associated Cross-Reactive Idiotypes in Iranian Seropositive and Seronegative Patients with Rheumatoid Arthritis

High levels of rheumatoid factors (RF) are detectable in serum of the majority of patients with rheumatoid arthritis (RA), but 5-10% of patients remain seronegative (SN). Despite clinical and genetic similarities between these two subsets of RA, it has been proposed that they may be regarded as distinct clinical entities. Methods: In the present study a panel of monoclonal antibodies (mAb) rec...

Transfer factor in hyper - IgE syndrome 467

H. H. KESARWALA*, R. V. S. K. PRASADt, R. SZEP, E. OLDMAN, S. LANE & P. S. PAPAGEORGIOU The Department ofPediatrics, CMDHJ, Rutgers Medical School, Piscataway, New Jersey, * Division ofAllergy Immunology, Children's Hospital Medical Center, Elland and Bethesda Avenue, Cincinnati, Ohio 45229 and t Division ofAllergy, Department ofPediatrics, Children's Hospital ofMichigan, 3901 Beaubien Boulevar...